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Contrasting Modes of New World Arenavirus Neutralization by Immunization-Elicited Monoclonal Antibodies

Transmission of the New World hemorrhagic fever arenaviruses Junín virus (JUNV) and Machupo virus (MACV) to humans is facilitated, in part, by the interaction between the arenavirus GP1 glycoprotein and the human transferrin receptor 1 (hTfR1). We utilize a mouse model of live-attenuated immunizatio...

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Detalles Bibliográficos
Autores principales: Ng, Weng M., Sahin, Mehmet, Krumm, Stefanie A., Seow, Jeffrey, Zeltina, Antra, Harlos, Karl, Paesen, Guido C., Pinschewer, Daniel D., Doores, Katie J., Bowden, Thomas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9040744/
https://www.ncbi.nlm.nih.gov/pubmed/35315691
http://dx.doi.org/10.1128/mbio.02650-21

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