Cargando…
Contrasting Modes of New World Arenavirus Neutralization by Immunization-Elicited Monoclonal Antibodies
Transmission of the New World hemorrhagic fever arenaviruses Junín virus (JUNV) and Machupo virus (MACV) to humans is facilitated, in part, by the interaction between the arenavirus GP1 glycoprotein and the human transferrin receptor 1 (hTfR1). We utilize a mouse model of live-attenuated immunizatio...
Autores principales: | Ng, Weng M., Sahin, Mehmet, Krumm, Stefanie A., Seow, Jeffrey, Zeltina, Antra, Harlos, Karl, Paesen, Guido C., Pinschewer, Daniel D., Doores, Katie J., Bowden, Thomas A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9040744/ https://www.ncbi.nlm.nih.gov/pubmed/35315691 http://dx.doi.org/10.1128/mbio.02650-21 |
Ejemplares similares
-
Arenavirus Glycan Shield Promotes Neutralizing Antibody Evasion and Protracted Infection
por: Sommerstein, Rami, et al.
Publicado: (2015) -
The Janus Kinase Inhibitor Ruxolitinib Prevents Terminal Shock in a Mouse Model of Arenavirus Hemorrhagic Fever
por: Sahin, Mehmet, et al.
Publicado: (2021) -
Structural Basis for a Neutralizing Antibody Response Elicited by a Recombinant Hantaan Virus Gn Immunogen
por: Rissanen, Ilona, et al.
Publicado: (2021) -
Emerging Paramyxoviruses: Receptor Tropism and Zoonotic Potential
por: Zeltina, Antra, et al.
Publicado: (2016) -
Vaccine-elicited receptor-binding site antibodies neutralize two New World hemorrhagic fever arenaviruses
por: Clark, Lars E., et al.
Publicado: (2018)