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An Alanine Aminotransferase Is Required for Biofilm-Specific Resistance of Aspergillus fumigatus to Echinocandin Treatment

Alanine metabolism has been suggested as an adaptation strategy to oxygen limitation in organisms ranging from plants to mammals. Within the pulmonary infection microenvironment, Aspergillus fumigatus forms biofilms with steep oxygen gradients defined by regions of oxygen limitation. An alanine amin...

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Detalles Bibliográficos
Autores principales:	Kerkaert, Joshua D., Le Mauff, François, Wucher, Benjamin R., Beattie, Sarah R., Vesely, Elisa M., Sheppard, Donald C., Nadell, Carey D., Cramer, Robert A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9040767/ https://www.ncbi.nlm.nih.gov/pubmed/35254131 http://dx.doi.org/10.1128/mbio.02933-21

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