A Comprehensive Phenotypic Screening Strategy to Identify Modulators of Cargo Translocation by the Bacterial Type IVB Secretion System

Bacterial type IV secretion systems (T4SSs) are macromolecular machines that translocate effector proteins across multiple membranes into infected host cells. Loss of function mutations in genes encoding protein components of the T4SS render bacteria avirulent, highlighting the attractiveness of T4S...

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Detalles Bibliográficos
Autores principales: Cheng, Eric, Dorjsuren, Dorjbal, Lehman, Stephanie, Larson, Charles L., Titus, Steven A., Sun, Hongmao, Zakharov, Alexey, Rai, Ganesha, Heinzen, Robert A., Simeonov, Anton, Machner, Matthias P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9040768/
https://www.ncbi.nlm.nih.gov/pubmed/35258332
http://dx.doi.org/10.1128/mbio.00240-22

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