Cargando…

The SARS-CoV-2 B.1.618 variant slightly alters the spike RBD–ACE2 binding affinity and is an antibody escaping variant: a computational structural perspective

Continuing reports of new SARS-CoV-2 variants have caused worldwide concern and created a challenging situation for clinicians. The recently reported variant B.1.618, which possesses the E484K mutation specific to the receptor-binding domain (RBD), as well as two deletions of Tyr145 and His146 at th...

Descripción completa

Detalles Bibliográficos
Autores principales: Khan, Abbas, Gui, Jianjun, Ahmad, Waqar, Haq, Inamul, Shahid, Marukh, Khan, Awais Ahmed, Shah, Abdullah, Khan, Arsala, Ali, Liaqat, Anwar, Zeeshan, Safdar, Muhammad, Abubaker, Jehad, Uddin, N. Nizam, Cao, Liqiang, Wei, Dong-Qing, Mohammad, Anwar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9040812/
https://www.ncbi.nlm.nih.gov/pubmed/35480256
http://dx.doi.org/10.1039/d1ra04694b