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The SARS-CoV-2 B.1.618 variant slightly alters the spike RBD–ACE2 binding affinity and is an antibody escaping variant: a computational structural perspective
Continuing reports of new SARS-CoV-2 variants have caused worldwide concern and created a challenging situation for clinicians. The recently reported variant B.1.618, which possesses the E484K mutation specific to the receptor-binding domain (RBD), as well as two deletions of Tyr145 and His146 at th...
Autores principales: | Khan, Abbas, Gui, Jianjun, Ahmad, Waqar, Haq, Inamul, Shahid, Marukh, Khan, Awais Ahmed, Shah, Abdullah, Khan, Arsala, Ali, Liaqat, Anwar, Zeeshan, Safdar, Muhammad, Abubaker, Jehad, Uddin, N. Nizam, Cao, Liqiang, Wei, Dong-Qing, Mohammad, Anwar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9040812/ https://www.ncbi.nlm.nih.gov/pubmed/35480256 http://dx.doi.org/10.1039/d1ra04694b |
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