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CDK4/6 inhibitors: a brief overview and prospective research directions

The discovery of cyclin-dependent kinases (CDK) and their mechanism in regulating the cell cycle process was considered a game-changer in cancer therapy. Cell cycle arrest and apoptosis were both triggered by their inhibition. The CDK4/6 complex acts as a checkpoint during the cell cycle transition...

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Detalles Bibliográficos
Autores principales:	Adon, Tenzin, Shanmugarajan, Dhivya, Kumar, Honnavalli Yogish
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2021
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9040853/ https://www.ncbi.nlm.nih.gov/pubmed/35479560 http://dx.doi.org/10.1039/d1ra03820f

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