Visualizing Pyrazinamide Action by Live Single-Cell Imaging of Phagosome Acidification and Mycobacterium tuberculosis pH Homeostasis

Mycobacterium tuberculosis segregates within multiple subcellular niches with different biochemical and biophysical properties that, upon treatment, may impact antibiotic distribution, accumulation, and efficacy. However, it remains unclear whether fluctuating intracellular microenvironments alter m...

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Detalles Bibliográficos
Autores principales: Santucci, Pierre, Aylan, Beren, Botella, Laure, Bernard, Elliott M., Bussi, Claudio, Pellegrino, Enrica, Athanasiadi, Natalia, Gutierrez, Maximiliano G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9040869/
https://www.ncbi.nlm.nih.gov/pubmed/35323041
http://dx.doi.org/10.1128/mbio.00117-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9040869/
https://www.ncbi.nlm.nih.gov/pubmed/35323041
http://dx.doi.org/10.1128/mbio.00117-22

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