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Domino C–C/C–O bond formation: palladium-catalyzed regioselective synthesis of 7-iodobenzo[b]furans using 1,2,3-triiodobenzenes and benzylketones

A facile and efficient synthesis of 7-iodobenzo[b]furan derivatives via a highly regioselective tandem α-arylation/intramolecular O-arylation of 5-substituted-1,2,3-triiodobenzenes and benzylketones is described. Remarkably, the α-arylation coupling reactions initiate exclusively at the least steric...

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Detalles Bibliográficos
Autores principales: Al-Zoubi, Raed M., Al-Jammal, Walid K., Ferguson, Michael J., Murphy, Graham K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9040925/
https://www.ncbi.nlm.nih.gov/pubmed/35493993
http://dx.doi.org/10.1039/d1ra05730h