Layered double hydroxide-based nanocomposite scaffolds in tissue engineering applications

Layered double hydroxides (LDHs), when incorporated into biomaterials, provide a tunable composition, controllable particle size, anion exchange capacity, pH-sensitive solubility, high-drug loading efficiency, efficient gene and drug delivery, controlled release and effective intracellular uptake, n...

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Detalles Bibliográficos
Autores principales: Izbudak, Burcin, Cecen, Berivan, Anaya, Ingrid, Miri, Amir K., Bal-Ozturk, Ayca, Karaoz, Erdal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9041101/
https://www.ncbi.nlm.nih.gov/pubmed/35480250
http://dx.doi.org/10.1039/d1ra03978d
Descripción
Sumario:Layered double hydroxides (LDHs), when incorporated into biomaterials, provide a tunable composition, controllable particle size, anion exchange capacity, pH-sensitive solubility, high-drug loading efficiency, efficient gene and drug delivery, controlled release and effective intracellular uptake, natural biodegradability in an acidic medium, and negligible toxicity. In this review, we study potential applications of LDH-based nanocomposite scaffolds for tissue engineering. We address how LDHs provide new solutions for nanostructure stability and enhance in vivo studies' success.

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