Layered double hydroxide-based nanocomposite scaffolds in tissue engineering applications

Layered double hydroxides (LDHs), when incorporated into biomaterials, provide a tunable composition, controllable particle size, anion exchange capacity, pH-sensitive solubility, high-drug loading efficiency, efficient gene and drug delivery, controlled release and effective intracellular uptake, n...

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Detalles Bibliográficos
Autores principales: Izbudak, Burcin, Cecen, Berivan, Anaya, Ingrid, Miri, Amir K., Bal-Ozturk, Ayca, Karaoz, Erdal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9041101/
https://www.ncbi.nlm.nih.gov/pubmed/35480250
http://dx.doi.org/10.1039/d1ra03978d
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author Izbudak, Burcin
Cecen, Berivan
Anaya, Ingrid
Miri, Amir K.
Bal-Ozturk, Ayca
Karaoz, Erdal
author_facet Izbudak, Burcin
Cecen, Berivan
Anaya, Ingrid
Miri, Amir K.
Bal-Ozturk, Ayca
Karaoz, Erdal
author_sort Izbudak, Burcin
collection PubMed
description Layered double hydroxides (LDHs), when incorporated into biomaterials, provide a tunable composition, controllable particle size, anion exchange capacity, pH-sensitive solubility, high-drug loading efficiency, efficient gene and drug delivery, controlled release and effective intracellular uptake, natural biodegradability in an acidic medium, and negligible toxicity. In this review, we study potential applications of LDH-based nanocomposite scaffolds for tissue engineering. We address how LDHs provide new solutions for nanostructure stability and enhance in vivo studies' success.
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spelling pubmed-90411012022-04-26 Layered double hydroxide-based nanocomposite scaffolds in tissue engineering applications Izbudak, Burcin Cecen, Berivan Anaya, Ingrid Miri, Amir K. Bal-Ozturk, Ayca Karaoz, Erdal RSC Adv Chemistry Layered double hydroxides (LDHs), when incorporated into biomaterials, provide a tunable composition, controllable particle size, anion exchange capacity, pH-sensitive solubility, high-drug loading efficiency, efficient gene and drug delivery, controlled release and effective intracellular uptake, natural biodegradability in an acidic medium, and negligible toxicity. In this review, we study potential applications of LDH-based nanocomposite scaffolds for tissue engineering. We address how LDHs provide new solutions for nanostructure stability and enhance in vivo studies' success. The Royal Society of Chemistry 2021-09-09 /pmc/articles/PMC9041101/ /pubmed/35480250 http://dx.doi.org/10.1039/d1ra03978d Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Izbudak, Burcin
Cecen, Berivan
Anaya, Ingrid
Miri, Amir K.
Bal-Ozturk, Ayca
Karaoz, Erdal
Layered double hydroxide-based nanocomposite scaffolds in tissue engineering applications
title Layered double hydroxide-based nanocomposite scaffolds in tissue engineering applications
title_full Layered double hydroxide-based nanocomposite scaffolds in tissue engineering applications
title_fullStr Layered double hydroxide-based nanocomposite scaffolds in tissue engineering applications
title_full_unstemmed Layered double hydroxide-based nanocomposite scaffolds in tissue engineering applications
title_short Layered double hydroxide-based nanocomposite scaffolds in tissue engineering applications
title_sort layered double hydroxide-based nanocomposite scaffolds in tissue engineering applications
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9041101/
https://www.ncbi.nlm.nih.gov/pubmed/35480250
http://dx.doi.org/10.1039/d1ra03978d
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AT miriamirk layereddoublehydroxidebasednanocompositescaffoldsintissueengineeringapplications
AT balozturkayca layereddoublehydroxidebasednanocompositescaffoldsintissueengineeringapplications
AT karaozerdal layereddoublehydroxidebasednanocompositescaffoldsintissueengineeringapplications

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