Furan oxidation by Mn(iii)/Co(ii) catalysts – application to benzofuran synthesis

Furans containing a β-ketoester group at 2-position undergo oxidative ring-opening by Mn(iii)/Co(ii) catalysts under an O(2) atmosphere to produce 1,4-dicarbonyl moieties through an endoperoxide intermediate, which consecutively cyclized with the β-ketoester unit to afford 4-hydroxy-2-cyclohexen-1-o...

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Detalles Bibliográficos
Autores principales: Wang, Tingshu, Zhang, Miao, Zheng, Yifan, Seong, Junmo, Lah, Myoung Soo, Koo, Sangho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9041371/
https://www.ncbi.nlm.nih.gov/pubmed/35496848
http://dx.doi.org/10.1039/d1ra05305a
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author Wang, Tingshu
Zhang, Miao
Zheng, Yifan
Seong, Junmo
Lah, Myoung Soo
Koo, Sangho
author_facet Wang, Tingshu
Zhang, Miao
Zheng, Yifan
Seong, Junmo
Lah, Myoung Soo
Koo, Sangho
author_sort Wang, Tingshu
collection PubMed
description Furans containing a β-ketoester group at 2-position undergo oxidative ring-opening by Mn(iii)/Co(ii) catalysts under an O(2) atmosphere to produce 1,4-dicarbonyl moieties through an endoperoxide intermediate, which consecutively cyclized with the β-ketoester unit to afford 4-hydroxy-2-cyclohexen-1-ones. This oxidation/cyclization products were efficiently transformed into versatile benzofuran derivatives after consecutive aromatization and Paal–Knorr reaction.
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spelling pubmed-90413712022-04-28 Furan oxidation by Mn(iii)/Co(ii) catalysts – application to benzofuran synthesis Wang, Tingshu Zhang, Miao Zheng, Yifan Seong, Junmo Lah, Myoung Soo Koo, Sangho RSC Adv Chemistry Furans containing a β-ketoester group at 2-position undergo oxidative ring-opening by Mn(iii)/Co(ii) catalysts under an O(2) atmosphere to produce 1,4-dicarbonyl moieties through an endoperoxide intermediate, which consecutively cyclized with the β-ketoester unit to afford 4-hydroxy-2-cyclohexen-1-ones. This oxidation/cyclization products were efficiently transformed into versatile benzofuran derivatives after consecutive aromatization and Paal–Knorr reaction. The Royal Society of Chemistry 2021-09-22 /pmc/articles/PMC9041371/ /pubmed/35496848 http://dx.doi.org/10.1039/d1ra05305a Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Wang, Tingshu
Zhang, Miao
Zheng, Yifan
Seong, Junmo
Lah, Myoung Soo
Koo, Sangho
Furan oxidation by Mn(iii)/Co(ii) catalysts – application to benzofuran synthesis
title Furan oxidation by Mn(iii)/Co(ii) catalysts – application to benzofuran synthesis
title_full Furan oxidation by Mn(iii)/Co(ii) catalysts – application to benzofuran synthesis
title_fullStr Furan oxidation by Mn(iii)/Co(ii) catalysts – application to benzofuran synthesis
title_full_unstemmed Furan oxidation by Mn(iii)/Co(ii) catalysts – application to benzofuran synthesis
title_short Furan oxidation by Mn(iii)/Co(ii) catalysts – application to benzofuran synthesis
title_sort furan oxidation by mn(iii)/co(ii) catalysts – application to benzofuran synthesis
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9041371/
https://www.ncbi.nlm.nih.gov/pubmed/35496848
http://dx.doi.org/10.1039/d1ra05305a
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