A simple and efficient copper-catalyzed three-component reaction to synthesize (Z)-1,2-dihydro-2-iminoquinolines

A operationally simple synthesis of (Z)-1,2-dihydro-2-iminoquinolines that proceeds under mild conditions is achieved by copper-catalyzed reaction of 1-(2-aminophenyl)ethan-1-ones, sulfonyl azides and terminal ynones. In particular, the reaction goes through a base-free CuAAC/ring-opening process to...

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Detalles Bibliográficos
Autores principales: Luo, Xiai, Zhao, Yu, Tao, Susu, Yang, Zhong-Tao, Luo, Hui, Yang, Weiguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9041411/
https://www.ncbi.nlm.nih.gov/pubmed/35496874
http://dx.doi.org/10.1039/d1ra06330h
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author Luo, Xiai
Zhao, Yu
Tao, Susu
Yang, Zhong-Tao
Luo, Hui
Yang, Weiguang
author_facet Luo, Xiai
Zhao, Yu
Tao, Susu
Yang, Zhong-Tao
Luo, Hui
Yang, Weiguang
author_sort Luo, Xiai
collection PubMed
description A operationally simple synthesis of (Z)-1,2-dihydro-2-iminoquinolines that proceeds under mild conditions is achieved by copper-catalyzed reaction of 1-(2-aminophenyl)ethan-1-ones, sulfonyl azides and terminal ynones. In particular, the reaction goes through a base-free CuAAC/ring-opening process to obtain the Z-configured products due to hydrogen bonding.
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spelling pubmed-90414112022-04-28 A simple and efficient copper-catalyzed three-component reaction to synthesize (Z)-1,2-dihydro-2-iminoquinolines Luo, Xiai Zhao, Yu Tao, Susu Yang, Zhong-Tao Luo, Hui Yang, Weiguang RSC Adv Chemistry A operationally simple synthesis of (Z)-1,2-dihydro-2-iminoquinolines that proceeds under mild conditions is achieved by copper-catalyzed reaction of 1-(2-aminophenyl)ethan-1-ones, sulfonyl azides and terminal ynones. In particular, the reaction goes through a base-free CuAAC/ring-opening process to obtain the Z-configured products due to hydrogen bonding. The Royal Society of Chemistry 2021-09-29 /pmc/articles/PMC9041411/ /pubmed/35496874 http://dx.doi.org/10.1039/d1ra06330h Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Luo, Xiai
Zhao, Yu
Tao, Susu
Yang, Zhong-Tao
Luo, Hui
Yang, Weiguang
A simple and efficient copper-catalyzed three-component reaction to synthesize (Z)-1,2-dihydro-2-iminoquinolines
title A simple and efficient copper-catalyzed three-component reaction to synthesize (Z)-1,2-dihydro-2-iminoquinolines
title_full A simple and efficient copper-catalyzed three-component reaction to synthesize (Z)-1,2-dihydro-2-iminoquinolines
title_fullStr A simple and efficient copper-catalyzed three-component reaction to synthesize (Z)-1,2-dihydro-2-iminoquinolines
title_full_unstemmed A simple and efficient copper-catalyzed three-component reaction to synthesize (Z)-1,2-dihydro-2-iminoquinolines
title_short A simple and efficient copper-catalyzed three-component reaction to synthesize (Z)-1,2-dihydro-2-iminoquinolines
title_sort simple and efficient copper-catalyzed three-component reaction to synthesize (z)-1,2-dihydro-2-iminoquinolines
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9041411/
https://www.ncbi.nlm.nih.gov/pubmed/35496874
http://dx.doi.org/10.1039/d1ra06330h
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