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Transcriptional lockdown during acute proteotoxic stress
Cells experiencing proteotoxic stress downregulate the expression of thousands of active genes and upregulate a few stress-response genes. The strategy of downregulating gene expression has conceptual parallels with general lockdown in the global response to the coronavirus disease 2019 (COVID-19) p...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Elsevier Ltd.
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9041648/ https://www.ncbi.nlm.nih.gov/pubmed/35487807 http://dx.doi.org/10.1016/j.tibs.2022.03.020 |