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Catalytic approach to in vivo metabolism of atractylenolide III using biomimetic iron–porphyrin complexes

Atractylenolide III (AT-III) is a pharmacologically effective phytochemical and is known to be oxygenated during systemic metabolism mainly by cytochrome P450 enzymes (CYP450s), iron-containing porphyrin-based oxygenases. In rat plasma samples, the oxygenated metabolite of orally ingested AT-III was...

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Detalles Bibliográficos
Autores principales:	Lim, Hanae, Jeon, Hyeri, Hong, Seungwoo, Kim, Jung-Hoon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2021
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9042181/ https://www.ncbi.nlm.nih.gov/pubmed/35493574 http://dx.doi.org/10.1039/d1ra05014a

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