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Cation–π interactions drive hydrophobic self-assembly and aggregation of niclosamide in water

The beneficial medicinal effects of niclosamide have been reported to be hampered by poor aqueous solubility and so a higher concentration dosage is required. In this work, we have studied the aggregation properties of niclosamide in water by varying the number of monomers. We have employed all-atom...

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Detalles Bibliográficos
Autores principales: Vuai, Said A. H., Sahini, Mtabazi G., Onoka, Isaac, Kiruri, Lucy W., Shadrack, Daniel M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9042188/
https://www.ncbi.nlm.nih.gov/pubmed/35493563
http://dx.doi.org/10.1039/d1ra05358b