Prediction of Corresponding Dose of Transdermal Blonanserin to Oral Dose Based on Dopamine D(2) Receptor Occupancy: Unique Characteristics of Blonanserin Transdermal Patch

BACKGROUND/PURPOSE: Blonanserin is an atypical antipsychotic, a potent selective antagonist of dopamine D(2) receptor (D(2)), prescribed as oral formulations in patients with schizophrenia. Blonanserin transdermal patch was developed to provide a new treatment option, but the corresponding dose to o...

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Detalles Bibliográficos
Autores principales: Tomita, Yoshiko, Takagaki, Takeshi, Kitamura, Atsushi, Wada, Erika, Nishibe, Hironori, Tateno, Amane, Okubo, Yoshiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Original Contributions
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9042341/
https://www.ncbi.nlm.nih.gov/pubmed/35384896
http://dx.doi.org/10.1097/JCP.0000000000001545

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