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Enhancement of antibacterial function by incorporation of silver-doped ZnO nanocrystals onto a laser-induced graphene surface
Bacterial biofilms formed on touchable surfaces such as displays of electronic devices not only reduce the product service life, but also cause human health issues. There is an urgent need to research the biofilm formation mechanism and methodologies to prevent formation of biofilms on human touchab...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9042371/ https://www.ncbi.nlm.nih.gov/pubmed/35497311 http://dx.doi.org/10.1039/d1ra06390a |
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author | Wang, Liyong Wang, Zhenghao Wang, Zhiwen Zhang, Chunyang Wu, Yongling Zheng, Hongyu |
author_facet | Wang, Liyong Wang, Zhenghao Wang, Zhiwen Zhang, Chunyang Wu, Yongling Zheng, Hongyu |
author_sort | Wang, Liyong |
collection | PubMed |
description | Bacterial biofilms formed on touchable surfaces such as displays of electronic devices not only reduce the product service life, but also cause human health issues. There is an urgent need to research the biofilm formation mechanism and methodologies to prevent formation of biofilms on human touchable surfaces. It has been reported that laser-induced graphene (LIG) helps resist biofilm growth, which has been attributed to the atomic composition and sharp edges of graphene. However, LIG alone was not able to retard bacterial growth completely. It has been reported that LIG incorporated with silver (Ag) nanoparticles exhibited enhanced surface antibacterial activity. As a heavy metal, overdose of Ag is harmful to human health. Therefore, a new biocompatible antibacterial agent to replace or reduce the use of Ag is highly important. In this study, we investigate and compare the effect of LIG doped with two types of nanocrystals, i.e., ZnO and silver (Ag)-doped ZnO, on antibacterial actions. A 355 nm ultraviolet (UV) laser was used to produce LIG on a watercolor paper substrate. Formation of few-layer graphene has been verified by Raman spectra. Escherichia coli (E. coli), a representative of Gram-negative bacteria and Staphylococcus aureus (S. aureus), a representative of Gram-positive bacteria were employed for the investigation of the bacteriostatic properties of the LIG paper substrate. Results show that with the incorporation of either the ZnO nanocrystals or the silver (Ag)-doped ZnO nanocrystals into LIG, the antibacterial effect became stronger. It is further shown that the Ag-doped ZnO nanocrystals have superior antibacterial performance to that of the ZnO nanocrystals. The Ag-doped ZnO nanocrystals are potentially an effective and biocompatible antibacterial agent and yet have a much reduced and acceptable level of Ag concentration. |
format | Online Article Text |
id | pubmed-9042371 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | The Royal Society of Chemistry |
record_format | MEDLINE/PubMed |
spelling | pubmed-90423712022-04-28 Enhancement of antibacterial function by incorporation of silver-doped ZnO nanocrystals onto a laser-induced graphene surface Wang, Liyong Wang, Zhenghao Wang, Zhiwen Zhang, Chunyang Wu, Yongling Zheng, Hongyu RSC Adv Chemistry Bacterial biofilms formed on touchable surfaces such as displays of electronic devices not only reduce the product service life, but also cause human health issues. There is an urgent need to research the biofilm formation mechanism and methodologies to prevent formation of biofilms on human touchable surfaces. It has been reported that laser-induced graphene (LIG) helps resist biofilm growth, which has been attributed to the atomic composition and sharp edges of graphene. However, LIG alone was not able to retard bacterial growth completely. It has been reported that LIG incorporated with silver (Ag) nanoparticles exhibited enhanced surface antibacterial activity. As a heavy metal, overdose of Ag is harmful to human health. Therefore, a new biocompatible antibacterial agent to replace or reduce the use of Ag is highly important. In this study, we investigate and compare the effect of LIG doped with two types of nanocrystals, i.e., ZnO and silver (Ag)-doped ZnO, on antibacterial actions. A 355 nm ultraviolet (UV) laser was used to produce LIG on a watercolor paper substrate. Formation of few-layer graphene has been verified by Raman spectra. Escherichia coli (E. coli), a representative of Gram-negative bacteria and Staphylococcus aureus (S. aureus), a representative of Gram-positive bacteria were employed for the investigation of the bacteriostatic properties of the LIG paper substrate. Results show that with the incorporation of either the ZnO nanocrystals or the silver (Ag)-doped ZnO nanocrystals into LIG, the antibacterial effect became stronger. It is further shown that the Ag-doped ZnO nanocrystals have superior antibacterial performance to that of the ZnO nanocrystals. The Ag-doped ZnO nanocrystals are potentially an effective and biocompatible antibacterial agent and yet have a much reduced and acceptable level of Ag concentration. The Royal Society of Chemistry 2021-10-18 /pmc/articles/PMC9042371/ /pubmed/35497311 http://dx.doi.org/10.1039/d1ra06390a Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/ |
spellingShingle | Chemistry Wang, Liyong Wang, Zhenghao Wang, Zhiwen Zhang, Chunyang Wu, Yongling Zheng, Hongyu Enhancement of antibacterial function by incorporation of silver-doped ZnO nanocrystals onto a laser-induced graphene surface |
title | Enhancement of antibacterial function by incorporation of silver-doped ZnO nanocrystals onto a laser-induced graphene surface |
title_full | Enhancement of antibacterial function by incorporation of silver-doped ZnO nanocrystals onto a laser-induced graphene surface |
title_fullStr | Enhancement of antibacterial function by incorporation of silver-doped ZnO nanocrystals onto a laser-induced graphene surface |
title_full_unstemmed | Enhancement of antibacterial function by incorporation of silver-doped ZnO nanocrystals onto a laser-induced graphene surface |
title_short | Enhancement of antibacterial function by incorporation of silver-doped ZnO nanocrystals onto a laser-induced graphene surface |
title_sort | enhancement of antibacterial function by incorporation of silver-doped zno nanocrystals onto a laser-induced graphene surface |
topic | Chemistry |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9042371/ https://www.ncbi.nlm.nih.gov/pubmed/35497311 http://dx.doi.org/10.1039/d1ra06390a |
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