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Spatial distribution of isobaric androgens in target tissues using chemical derivatization and MALDI-2 on a trapped ion mobility quadrupole time-of-flight instrument

Prostate cancer is initially treated via androgen deprivation therapy (ADT), a highly successful treatment in the initial pursuit of tumour regression, but commonly restricted by the eventual emergence of a more lethal ‘castrate resistant’ (CRPC) form of the disease. Intracrine pathways that utilize...

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Detalles Bibliográficos
Autores principales:	Mackay, C. L. Logan, Soltwisch, Jens, Heijs, Bram, Smith, Karl W., Cruickshank, Faye L., Nyhuis, Annika, Dreisewerd, Klaus, Cobice, Diego
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2021
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9042386/ https://www.ncbi.nlm.nih.gov/pubmed/35497310 http://dx.doi.org/10.1039/d1ra06086d

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