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Efficient CRISPR/Cas9-mediated gene disruption in the tetraploid protist Giardia intestinalis

CRISPR/Cas9-mediated genome editing has become an extremely powerful technique used to modify gene expression in many organisms, including parasitic protists. Giardia intestinalis, a protist parasite that infects approximately 280 million people around the world each year, has been eluding the use o...

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Detalles Bibliográficos
Autores principales: Horáčková, Vendula, Voleman, Luboš, Hagen, Kari D., Petrů, Markéta, Vinopalová, Martina, Weisz, Filip, Janowicz, Natalia, Marková, Lenka, Motyčková, Alžběta, Najdrová, Vladimíra, Tůmová, Pavla, Dawson, Scott C., Doležal, Pavel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9042576/
https://www.ncbi.nlm.nih.gov/pubmed/35472287
http://dx.doi.org/10.1098/rsob.210361