Liquid-to-solid phase transition of oskar ribonucleoprotein granules is essential for their function in Drosophila embryonic development

Asymmetric localization of oskar ribonucleoprotein (RNP) granules to the oocyte posterior is crucial for abdominal patterning and germline formation in the Drosophila embryo. We show that oskar RNP granules in the oocyte are condensates with solid-like physical properties. Using purified oskar RNA a...

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Detalles Bibliográficos
Autores principales: Bose, Mainak, Lampe, Marko, Mahamid, Julia, Ephrussi, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9042795/
https://www.ncbi.nlm.nih.gov/pubmed/35325593
http://dx.doi.org/10.1016/j.cell.2022.02.022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9042795/
https://www.ncbi.nlm.nih.gov/pubmed/35325593
http://dx.doi.org/10.1016/j.cell.2022.02.022

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