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Liquid-to-solid phase transition of oskar ribonucleoprotein granules is essential for their function in Drosophila embryonic development
Asymmetric localization of oskar ribonucleoprotein (RNP) granules to the oocyte posterior is crucial for abdominal patterning and germline formation in the Drosophila embryo. We show that oskar RNP granules in the oocyte are condensates with solid-like physical properties. Using purified oskar RNA a...
Autores principales: | Bose, Mainak, Lampe, Marko, Mahamid, Julia, Ephrussi, Anne |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9042795/ https://www.ncbi.nlm.nih.gov/pubmed/35325593 http://dx.doi.org/10.1016/j.cell.2022.02.022 |
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