Circle‐Seq reveals genomic and disease‐specific hallmarks in urinary cell‐free extrachromosomal circular DNAs

BACKGROUND: Extrachromosomal circular deoxyribonucleic acid (eccDNA) is evolving as a valuable biomarker, while little is known about its presence in urine. METHODS: Here, we report the discovery and analysis of urinary cell‐free eccDNAs (ucf‐eccDNAs) in healthy controls and patients with advanced c...

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Detalles Bibliográficos
Autores principales: Lv, Wei, Pan, Xiaoguang, Han, Peng, Wang, Ziyu, Feng, Weijia, Xing, Xue, Wang, Qingqing, Qu, Kunli, Zeng, Yuchen, Zhang, Cailin, Xu, Zhe, Li, Yi, Zheng, Tianyu, Lin, Ling, Liu, Chengxun, Liu, Xuemei, Li, Hanbo, Henriksen, Rasmus Amund, Bolund, Lars, Lin, Lin, Jin, Xin, Yang, Huanming, Zhang, Xiuqing, Yin, Tailang, Regenberg, Birgitte, He, Fan, Luo, Yonglun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9042798/
https://www.ncbi.nlm.nih.gov/pubmed/35474296
http://dx.doi.org/10.1002/ctm2.817

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