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Polyfluoroalkylated antipyrines in Pd-catalyzed transformations
In the direct C–H arylation with arylhalogenides in the presence of Pd(OAc)(2), trifluoromethyl-containing antipyrine reacts very slowly and incompletely owing to the low nucleophilicity of its C4 center. However, it was effective in modifying polyfluoroalkyl-substituted 4-bromo- and 4-iodo antipyri...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society of Chemistry
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9042801/ https://www.ncbi.nlm.nih.gov/pubmed/35493195 http://dx.doi.org/10.1039/d1ra06967e |