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TLR2/caspase-5/Panx1 pathway mediates necrosis-induced NLRP3 inflammasome activation in macrophages during acute kidney injury

Acute kidney injury (AKI) is characterized by necroinflammation formed by necrotic tubular epithelial cells (TECs) and interstitial inflammation. In necroinflammation, macrophages are key inflammatory cells and can be activated and polarized into proinflammatory macrophages. Membranous Toll-like rec...

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Detalles Bibliográficos
Autores principales:	Liu, Chongbin, Shen, Yanting, Huang, Liuwei, Wang, Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9042857/ https://www.ncbi.nlm.nih.gov/pubmed/35473933 http://dx.doi.org/10.1038/s41420-022-01032-2

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