Two DNA vaccines protect against severe disease and pathology due to SARS-CoV-2 in Syrian hamsters

The SARS-CoV-2 pandemic is an ongoing threat to global health, and wide-scale vaccination is an efficient method to reduce morbidity and mortality. We designed and evaluated two DNA plasmid vaccines, based on the pIDV-II system, expressing the SARS-CoV-2 spike gene, with or without an immunogenic pe...

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Detalles Bibliográficos
Autores principales: Babuadze, George Giorgi, Fausther-Bovendo, Hugues, deLaVega, Marc-Antoine, Lillie, Brandon, Naghibosadat, Maedeh, Shahhosseini, Nariman, Joyce, Michael A., Saffran, Holly A., Lorne Tyrrell, D., Falzarano, Darryl, Senthilkumaran, Chandrika, Christie-Holmes, Natasha, Ahn, Steven, Gray-Owen, Scott D., Banerjee, Arinjay, Mubareka, Samira, Mossman, Karen, Dupont, Chanel, Pedersen, Jannie, Lafrance, Mark-Alexandre, Kobinger, Gary P., Kozak, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9042934/
https://www.ncbi.nlm.nih.gov/pubmed/35474311
http://dx.doi.org/10.1038/s41541-022-00461-5

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