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Optocapacitance: physical basis and its application
The observation that membrane capacitance increases with temperature has led to the development of new methods of neuronal stimulation using light. The optocapacitive effect refers to a light-induced change in capacitance produced by the heating of the membrane through a photothermal effect. This ch...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9042976/ https://www.ncbi.nlm.nih.gov/pubmed/35528029 http://dx.doi.org/10.1007/s12551-022-00943-9 |
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author | Pinto, Bernardo I. Bassetto, Carlos A. Z. Bezanilla, Francisco |
author_facet | Pinto, Bernardo I. Bassetto, Carlos A. Z. Bezanilla, Francisco |
author_sort | Pinto, Bernardo I. |
collection | PubMed |
description | The observation that membrane capacitance increases with temperature has led to the development of new methods of neuronal stimulation using light. The optocapacitive effect refers to a light-induced change in capacitance produced by the heating of the membrane through a photothermal effect. This change in capacitance manifests as a current, named optocapacitive current that depolarizes cells and therefore can be used to stimulate excitable tissues. Here, we discuss how optocapacitance arises from basic membrane properties, the characteristics of the optocapacitive current, its use for neuronal stimulation, and the challenges for its application in vivo. |
format | Online Article Text |
id | pubmed-9042976 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Springer Berlin Heidelberg |
record_format | MEDLINE/PubMed |
spelling | pubmed-90429762022-05-07 Optocapacitance: physical basis and its application Pinto, Bernardo I. Bassetto, Carlos A. Z. Bezanilla, Francisco Biophys Rev Issue Focus Costa Rican Biophysics • Review The observation that membrane capacitance increases with temperature has led to the development of new methods of neuronal stimulation using light. The optocapacitive effect refers to a light-induced change in capacitance produced by the heating of the membrane through a photothermal effect. This change in capacitance manifests as a current, named optocapacitive current that depolarizes cells and therefore can be used to stimulate excitable tissues. Here, we discuss how optocapacitance arises from basic membrane properties, the characteristics of the optocapacitive current, its use for neuronal stimulation, and the challenges for its application in vivo. Springer Berlin Heidelberg 2022-04-13 /pmc/articles/PMC9042976/ /pubmed/35528029 http://dx.doi.org/10.1007/s12551-022-00943-9 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Issue Focus Costa Rican Biophysics • Review Pinto, Bernardo I. Bassetto, Carlos A. Z. Bezanilla, Francisco Optocapacitance: physical basis and its application |
title | Optocapacitance: physical basis and its application |
title_full | Optocapacitance: physical basis and its application |
title_fullStr | Optocapacitance: physical basis and its application |
title_full_unstemmed | Optocapacitance: physical basis and its application |
title_short | Optocapacitance: physical basis and its application |
title_sort | optocapacitance: physical basis and its application |
topic | Issue Focus Costa Rican Biophysics • Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9042976/ https://www.ncbi.nlm.nih.gov/pubmed/35528029 http://dx.doi.org/10.1007/s12551-022-00943-9 |
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