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Roxadustat Attenuates the Disruption of Epithelial Tight Junction in Caco2 Cells and a Rat Model of CKD Through MicroRNA-223

INTRODUCTION: Increasing evidence supports the idea that the disruption of epithelial tight junction proteins (TJPs) caused by accumulation of uremia toxins, such as homocysteine (Hcy), is one of the most important mechanisms underlying the damage of intestinal barrier function (IBF) in chronic kidn...

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Detalles Bibliográficos
Autores principales:	Qu, Ning, Chen, Lei, Liang, Shanshan, Wei, Meng, Sun, Lingshuang, He, Quan, Xue, Jinhong, Wang, Meng, Shi, Kehui, Jiang, Hongli, Liu, Hua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9043115/ https://www.ncbi.nlm.nih.gov/pubmed/35492370 http://dx.doi.org/10.3389/fmed.2022.850966

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