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Self-adjuvanting nanovaccines boost lung-resident CD4(+) T cell immune responses in BCG-primed mice

Heterologous vaccine regimens could extend waning protection in the global population immunized with Mycobacterium bovis Bacille Calmette-Guerin (BCG). We demonstrate that pulmonary delivery of peptide nanofibers (PNFs) bearing an Ag85B CD4(+) T cell epitope increased the frequency of antigen-specif...

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Detalles Bibliográficos
Autores principales:	Files, Megan A., Naqvi, Kubra F., Saito, Tais B., Clover, Tara M., Rudra, Jai S., Endsley, Janice J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9043212/ https://www.ncbi.nlm.nih.gov/pubmed/35474079 http://dx.doi.org/10.1038/s41541-022-00466-0

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