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Advanced Neuroimaging Role in Traumatic Brain Injury: A Narrative Review

Traumatic brain injury (TBI) is a common source of morbidity and mortality among civilians and military personnel. Initial routine neuroimaging plays an essential role in rapidly assessing intracranial injury that may require intervention. However, in the context of TBI, limitations of routine neuro...

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Autores principales: Hu, Ling, Yang, Siyu, Jin, Bo, Wang, Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9043279/
https://www.ncbi.nlm.nih.gov/pubmed/35495065
http://dx.doi.org/10.3389/fnins.2022.872609
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author Hu, Ling
Yang, Siyu
Jin, Bo
Wang, Chao
author_facet Hu, Ling
Yang, Siyu
Jin, Bo
Wang, Chao
author_sort Hu, Ling
collection PubMed
description Traumatic brain injury (TBI) is a common source of morbidity and mortality among civilians and military personnel. Initial routine neuroimaging plays an essential role in rapidly assessing intracranial injury that may require intervention. However, in the context of TBI, limitations of routine neuroimaging include poor visualization of more subtle changes of brain parenchymal after injury, poor prognostic ability and inability to analyze cerebral perfusion, metabolite and mechanical properties. With the development of modern neuroimaging techniques, advanced neuroimaging techniques have greatly boosted the studies in the diagnosis, prognostication, and eventually impacting treatment of TBI. Advances in neuroimaging techniques have shown potential, including (1) Ultrasound (US) based techniques (contrast-enhanced US, intravascular US, and US elastography), (2) Magnetic resonance imaging (MRI) based techniques (diffusion tensor imaging, magnetic resonance spectroscopy, perfusion weighted imaging, magnetic resonance elastography and functional MRI), and (3) molecular imaging based techniques (positron emission tomography and single photon emission computed tomography). Therefore, in this review, we aim to summarize the role of these advanced neuroimaging techniques in the evaluation and management of TBI. This review is the first to combine the role of the US, MRI and molecular imaging based techniques in TBI. Advanced neuroimaging techniques have great potential; still, there is much to improve. With more clinical validation and larger studies, these techniques will be likely applied for routine clinical use from the initial research.
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spelling pubmed-90432792022-04-28 Advanced Neuroimaging Role in Traumatic Brain Injury: A Narrative Review Hu, Ling Yang, Siyu Jin, Bo Wang, Chao Front Neurosci Neuroscience Traumatic brain injury (TBI) is a common source of morbidity and mortality among civilians and military personnel. Initial routine neuroimaging plays an essential role in rapidly assessing intracranial injury that may require intervention. However, in the context of TBI, limitations of routine neuroimaging include poor visualization of more subtle changes of brain parenchymal after injury, poor prognostic ability and inability to analyze cerebral perfusion, metabolite and mechanical properties. With the development of modern neuroimaging techniques, advanced neuroimaging techniques have greatly boosted the studies in the diagnosis, prognostication, and eventually impacting treatment of TBI. Advances in neuroimaging techniques have shown potential, including (1) Ultrasound (US) based techniques (contrast-enhanced US, intravascular US, and US elastography), (2) Magnetic resonance imaging (MRI) based techniques (diffusion tensor imaging, magnetic resonance spectroscopy, perfusion weighted imaging, magnetic resonance elastography and functional MRI), and (3) molecular imaging based techniques (positron emission tomography and single photon emission computed tomography). Therefore, in this review, we aim to summarize the role of these advanced neuroimaging techniques in the evaluation and management of TBI. This review is the first to combine the role of the US, MRI and molecular imaging based techniques in TBI. Advanced neuroimaging techniques have great potential; still, there is much to improve. With more clinical validation and larger studies, these techniques will be likely applied for routine clinical use from the initial research. Frontiers Media S.A. 2022-04-13 /pmc/articles/PMC9043279/ /pubmed/35495065 http://dx.doi.org/10.3389/fnins.2022.872609 Text en Copyright © 2022 Hu, Yang, Jin and Wang. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neuroscience
Hu, Ling
Yang, Siyu
Jin, Bo
Wang, Chao
Advanced Neuroimaging Role in Traumatic Brain Injury: A Narrative Review
title Advanced Neuroimaging Role in Traumatic Brain Injury: A Narrative Review
title_full Advanced Neuroimaging Role in Traumatic Brain Injury: A Narrative Review
title_fullStr Advanced Neuroimaging Role in Traumatic Brain Injury: A Narrative Review
title_full_unstemmed Advanced Neuroimaging Role in Traumatic Brain Injury: A Narrative Review
title_short Advanced Neuroimaging Role in Traumatic Brain Injury: A Narrative Review
title_sort advanced neuroimaging role in traumatic brain injury: a narrative review
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9043279/
https://www.ncbi.nlm.nih.gov/pubmed/35495065
http://dx.doi.org/10.3389/fnins.2022.872609
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