A Pro-Endocrine Pancreatic Islet Transcriptional Program Established During Development Is Retained in Human Gallbladder Epithelial Cells

BACKGROUND & AIMS: Pancreatic islet β-cells are factories for insulin production; however, ectopic expression of insulin also is well recognized. The gallbladder is a next-door neighbor to the developing pancreas. Here, we wanted to understand if gallbladders contain functional insulin-producing...

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Detalles Bibliográficos
Autores principales: Joglekar, Mugdha V., Sahu, Subhshri, Wong, Wilson K.M., Satoor, Sarang N., Dong, Charlotte X., Farr, Ryan J., Williams, Michael D., Pandya, Prapti, Jhala, Gaurang, Yang, Sundy N.Y., Chew, Yi Vee, Hetherington, Nicola, Thiruchevlam, Dhan, Mitnala, Sasikala, Rao, Guduru V., Reddy, Duvvuru Nageshwar, Loudovaris, Thomas, Hawthorne, Wayne J., Elefanty, Andrew G., Joglekar, Vinay M., Stanley, Edouard G., Martin, David, Thomas, Helen E., Tosh, David, Dalgaard, Louise T., Hardikar, Anandwardhan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9043310/
https://www.ncbi.nlm.nih.gov/pubmed/35032693
http://dx.doi.org/10.1016/j.jcmgh.2022.01.008

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