Photo-triggered cargo release from liposome chlorin e6-bearing pullulan hybrid nanoparticles via membrane permeabilization

A liposome chlorin e6-bearing pullulan nanogel hybrid was prepared as a light-triggered payload release platform. The current system enabled manipulation of the release profile of model drugs encapsulated by liposomes. Gelatin hydrogels that comprised hybrid nanoparticles could successfully control...

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Detalles Bibliográficos
Autores principales: Kawasaki, Riku, Ohdake, Reo, Eto, Takuro, Yamana, Keita, Nakaya, Toshimi, Ishida, Takenori, Kuroda, Akio, Ikeda, Atsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9043425/
https://www.ncbi.nlm.nih.gov/pubmed/35494347
http://dx.doi.org/10.1039/d1ra07807k
Descripción
Sumario:A liposome chlorin e6-bearing pullulan nanogel hybrid was prepared as a light-triggered payload release platform. The current system enabled manipulation of the release profile of model drugs encapsulated by liposomes. Gelatin hydrogels that comprised hybrid nanoparticles could successfully control the delivery of cargo molecules to human mesenchymal stem cells with light stimuli without injury to the cells.

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