One-pot analysis of enantiomeric excess of free amino acids by electrospray ionization mass spectrometry

An electrospray ionization mass spectrometric method for the simultaneous analysis of the enantiomeric excess of free amino acids, without chromatographic separation, was demonstrated using a quasi-racemic mixture of deuterium-labelled and unlabelled chiral copper(ii) complexes. This convenient meth...

Descripción completa

Detalles Bibliográficos
Autores principales: Nakakoji, Takashi, Sato, Hirofumi, Ono, Daisuke, Miyake, Hiroyuki, Mieda, Eiko, Shinoda, Satoshi, Tsukube, Hiroshi, Kawasaki, Hideya, Arakawa, Ryuichi, Shizuma, Motohiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9043479/
https://www.ncbi.nlm.nih.gov/pubmed/35492793
http://dx.doi.org/10.1039/d1ra06542d
Descripción
Sumario:An electrospray ionization mass spectrometric method for the simultaneous analysis of the enantiomeric excess of free amino acids, without chromatographic separation, was demonstrated using a quasi-racemic mixture of deuterium-labelled and unlabelled chiral copper(ii) complexes. This convenient method enables the simultaneous high-sensitivity determination of the enantiomeric excess of 12 amino acids.

Ejemplares similares