One-pot analysis of enantiomeric excess of free amino acids by electrospray ionization mass spectrometry

An electrospray ionization mass spectrometric method for the simultaneous analysis of the enantiomeric excess of free amino acids, without chromatographic separation, was demonstrated using a quasi-racemic mixture of deuterium-labelled and unlabelled chiral copper(ii) complexes. This convenient meth...

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Detalles Bibliográficos
Autores principales: Nakakoji, Takashi, Sato, Hirofumi, Ono, Daisuke, Miyake, Hiroyuki, Mieda, Eiko, Shinoda, Satoshi, Tsukube, Hiroshi, Kawasaki, Hideya, Arakawa, Ryuichi, Shizuma, Motohiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9043479/
https://www.ncbi.nlm.nih.gov/pubmed/35492793
http://dx.doi.org/10.1039/d1ra06542d
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author Nakakoji, Takashi
Sato, Hirofumi
Ono, Daisuke
Miyake, Hiroyuki
Mieda, Eiko
Shinoda, Satoshi
Tsukube, Hiroshi
Kawasaki, Hideya
Arakawa, Ryuichi
Shizuma, Motohiro
author_facet Nakakoji, Takashi
Sato, Hirofumi
Ono, Daisuke
Miyake, Hiroyuki
Mieda, Eiko
Shinoda, Satoshi
Tsukube, Hiroshi
Kawasaki, Hideya
Arakawa, Ryuichi
Shizuma, Motohiro
author_sort Nakakoji, Takashi
collection PubMed
description An electrospray ionization mass spectrometric method for the simultaneous analysis of the enantiomeric excess of free amino acids, without chromatographic separation, was demonstrated using a quasi-racemic mixture of deuterium-labelled and unlabelled chiral copper(ii) complexes. This convenient method enables the simultaneous high-sensitivity determination of the enantiomeric excess of 12 amino acids.
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spelling pubmed-90434792022-04-28 One-pot analysis of enantiomeric excess of free amino acids by electrospray ionization mass spectrometry Nakakoji, Takashi Sato, Hirofumi Ono, Daisuke Miyake, Hiroyuki Mieda, Eiko Shinoda, Satoshi Tsukube, Hiroshi Kawasaki, Hideya Arakawa, Ryuichi Shizuma, Motohiro RSC Adv Chemistry An electrospray ionization mass spectrometric method for the simultaneous analysis of the enantiomeric excess of free amino acids, without chromatographic separation, was demonstrated using a quasi-racemic mixture of deuterium-labelled and unlabelled chiral copper(ii) complexes. This convenient method enables the simultaneous high-sensitivity determination of the enantiomeric excess of 12 amino acids. The Royal Society of Chemistry 2021-11-10 /pmc/articles/PMC9043479/ /pubmed/35492793 http://dx.doi.org/10.1039/d1ra06542d Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Nakakoji, Takashi
Sato, Hirofumi
Ono, Daisuke
Miyake, Hiroyuki
Mieda, Eiko
Shinoda, Satoshi
Tsukube, Hiroshi
Kawasaki, Hideya
Arakawa, Ryuichi
Shizuma, Motohiro
One-pot analysis of enantiomeric excess of free amino acids by electrospray ionization mass spectrometry
title One-pot analysis of enantiomeric excess of free amino acids by electrospray ionization mass spectrometry
title_full One-pot analysis of enantiomeric excess of free amino acids by electrospray ionization mass spectrometry
title_fullStr One-pot analysis of enantiomeric excess of free amino acids by electrospray ionization mass spectrometry
title_full_unstemmed One-pot analysis of enantiomeric excess of free amino acids by electrospray ionization mass spectrometry
title_short One-pot analysis of enantiomeric excess of free amino acids by electrospray ionization mass spectrometry
title_sort one-pot analysis of enantiomeric excess of free amino acids by electrospray ionization mass spectrometry
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9043479/
https://www.ncbi.nlm.nih.gov/pubmed/35492793
http://dx.doi.org/10.1039/d1ra06542d
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