Peroxidasin Deficiency Re-programs Macrophages Toward Pro-fibrolysis Function and Promotes Collagen Resolution in Liver

BACKGROUND & AIMS: During liver fibrosis, tissue repair mechanisms replace necrotic tissue with highly stabilized extracellular matrix proteins. Extracellular matrix stabilization influences the speed of tissue recovery. Here, we studied the expression and function of peroxidasin (PXDN), a perox...

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Detalles Bibliográficos
Autores principales: Sojoodi, Mozhdeh, Erstad, Derek J., Barrett, Stephen C., Salloum, Shadi, Zhu, Shijia, Qian, Tongqi, Colon, Selene, Gale, Eric M., Jordan, Veronica Clavijo, Wang, Yongtao, Li, Shen, Ataeinia, Bahar, Jalilifiroozinezhad, Sasan, Lanuti, Michael, Zukerberg, Lawrence, Caravan, Peter, Hoshida, Yujin, Chung, Raymond T., Bhave, Gautam, Lauer, Georg M., Fuchs, Bryan C., Tanabe, Kenneth K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9043497/
https://www.ncbi.nlm.nih.gov/pubmed/35093588
http://dx.doi.org/10.1016/j.jcmgh.2022.01.015

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