Aerobic copper-promoted oxidative dehydrosulfurative carbon–oxygen cross-coupling of 3,4-dihydropyrimidine-1H-2-thiones with alcohols

An aerobic Cu-promoted oxidative dehydrosulfurative carbon–oxygen cross-coupling of 3,4-dihydropyrimidin-1H-2-thiones (DHPMs) with both aliphatic and aromatic alcohols is described. Together with the ready availability of DHPMs and both alcohols, the method furnishes facile access to biologically va...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, Jihong, Kwon, Yujeong, Lee, Dong-Chan, Sohn, Jeong-Hun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9043584/
https://www.ncbi.nlm.nih.gov/pubmed/35494373
http://dx.doi.org/10.1039/d1ra07713a
_version_ 1784694914284519424
author Lee, Jihong
Kwon, Yujeong
Lee, Dong-Chan
Sohn, Jeong-Hun
author_facet Lee, Jihong
Kwon, Yujeong
Lee, Dong-Chan
Sohn, Jeong-Hun
author_sort Lee, Jihong
collection PubMed
description An aerobic Cu-promoted oxidative dehydrosulfurative carbon–oxygen cross-coupling of 3,4-dihydropyrimidin-1H-2-thiones (DHPMs) with both aliphatic and aromatic alcohols is described. Together with the ready availability of DHPMs and both alcohols, the method furnishes facile access to biologically valuable 2-alkoxypyrimidines with rapid diversification.
format Online
Article
Text
id pubmed-9043584
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher The Royal Society of Chemistry
record_format MEDLINE/PubMed
spelling pubmed-90435842022-04-28 Aerobic copper-promoted oxidative dehydrosulfurative carbon–oxygen cross-coupling of 3,4-dihydropyrimidine-1H-2-thiones with alcohols Lee, Jihong Kwon, Yujeong Lee, Dong-Chan Sohn, Jeong-Hun RSC Adv Chemistry An aerobic Cu-promoted oxidative dehydrosulfurative carbon–oxygen cross-coupling of 3,4-dihydropyrimidin-1H-2-thiones (DHPMs) with both aliphatic and aromatic alcohols is described. Together with the ready availability of DHPMs and both alcohols, the method furnishes facile access to biologically valuable 2-alkoxypyrimidines with rapid diversification. The Royal Society of Chemistry 2021-11-17 /pmc/articles/PMC9043584/ /pubmed/35494373 http://dx.doi.org/10.1039/d1ra07713a Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by/3.0/
spellingShingle Chemistry
Lee, Jihong
Kwon, Yujeong
Lee, Dong-Chan
Sohn, Jeong-Hun
Aerobic copper-promoted oxidative dehydrosulfurative carbon–oxygen cross-coupling of 3,4-dihydropyrimidine-1H-2-thiones with alcohols
title Aerobic copper-promoted oxidative dehydrosulfurative carbon–oxygen cross-coupling of 3,4-dihydropyrimidine-1H-2-thiones with alcohols
title_full Aerobic copper-promoted oxidative dehydrosulfurative carbon–oxygen cross-coupling of 3,4-dihydropyrimidine-1H-2-thiones with alcohols
title_fullStr Aerobic copper-promoted oxidative dehydrosulfurative carbon–oxygen cross-coupling of 3,4-dihydropyrimidine-1H-2-thiones with alcohols
title_full_unstemmed Aerobic copper-promoted oxidative dehydrosulfurative carbon–oxygen cross-coupling of 3,4-dihydropyrimidine-1H-2-thiones with alcohols
title_short Aerobic copper-promoted oxidative dehydrosulfurative carbon–oxygen cross-coupling of 3,4-dihydropyrimidine-1H-2-thiones with alcohols
title_sort aerobic copper-promoted oxidative dehydrosulfurative carbon–oxygen cross-coupling of 3,4-dihydropyrimidine-1h-2-thiones with alcohols
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9043584/
https://www.ncbi.nlm.nih.gov/pubmed/35494373
http://dx.doi.org/10.1039/d1ra07713a
work_keys_str_mv AT leejihong aerobiccopperpromotedoxidativedehydrosulfurativecarbonoxygencrosscouplingof34dihydropyrimidine1h2thioneswithalcohols
AT kwonyujeong aerobiccopperpromotedoxidativedehydrosulfurativecarbonoxygencrosscouplingof34dihydropyrimidine1h2thioneswithalcohols
AT leedongchan aerobiccopperpromotedoxidativedehydrosulfurativecarbonoxygencrosscouplingof34dihydropyrimidine1h2thioneswithalcohols
AT sohnjeonghun aerobiccopperpromotedoxidativedehydrosulfurativecarbonoxygencrosscouplingof34dihydropyrimidine1h2thioneswithalcohols

Ejemplares similares