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Acute intestinal pseudo-obstruction by pheochromocytoma: A case report with review of literature
INTRODUCTION: Pheochromocytomas are rare tumors of the adrenal gland. Intestinal pseudo-obstruction is a very rare presentation of a functioning catecholamine-secreting tumor. We present a case of intestinal pseudo-obstruction due to a large functioning pheochromocytoma. CASE REPORT: A 29-year-old f...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9043669/ https://www.ncbi.nlm.nih.gov/pubmed/35447562 http://dx.doi.org/10.1016/j.ijscr.2022.107008 |
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author | Bapir, Rawa Ahmed, Shaho F. Gharib, Soran Mohammeed Qader, Deedar Kakamad, Fahmi H. Popov, Elenko Buchholz, Noor Salih, Abduwahid M. |
author_facet | Bapir, Rawa Ahmed, Shaho F. Gharib, Soran Mohammeed Qader, Deedar Kakamad, Fahmi H. Popov, Elenko Buchholz, Noor Salih, Abduwahid M. |
author_sort | Bapir, Rawa |
collection | PubMed |
description | INTRODUCTION: Pheochromocytomas are rare tumors of the adrenal gland. Intestinal pseudo-obstruction is a very rare presentation of a functioning catecholamine-secreting tumor. We present a case of intestinal pseudo-obstruction due to a large functioning pheochromocytoma. CASE REPORT: A 29-year-old female presented with abdominal distension, pain, nausea, and vomiting with constipation for 3 weeks. She was hypertensive and diabetic and was on multiple medications. She reported frequent spells of severe headaches, palpitations, night sweats, and a 17 kg weight loss over 6 months. She had pallor, dyspnea, marked abdominal distension, and diminished bowel sounds. Her blood pressure was high at 200/120 mmHg. She had tachycardia (pulse 120 bpm) and tachypnea (35 pm). Serum metanephrine levels were significantly elevated, measuring 1203 pg/ml. Abdominal CT showed a heterogeneous, hyper-vascular mass near the upper pole of the left kidney, measuring 10.75 cm × 8.72 cm. Open left adrenalectomy was performed through an anterior subcostal approach to remove the tumor with the left adrenal gland. Histopathological examinations were consistent with pheochromocytoma. DISCUSSION: Some authors documented the correlation between tumor size and metabolic activity of catecholamine-secreting tumors with intestinal pseudo-obstruction by paralytic ileus. This case corresponds with these findings, with a tumor mass of 350 g and a serum metanephrine level of 1203 pg/ml. CONCLUSION: Although it is extremely rare, functioning pheochomocytoma could be a cause of instestinal obstruction or pseudo-obstruction. |
format | Online Article Text |
id | pubmed-9043669 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-90436692022-04-28 Acute intestinal pseudo-obstruction by pheochromocytoma: A case report with review of literature Bapir, Rawa Ahmed, Shaho F. Gharib, Soran Mohammeed Qader, Deedar Kakamad, Fahmi H. Popov, Elenko Buchholz, Noor Salih, Abduwahid M. Int J Surg Case Rep Case Report INTRODUCTION: Pheochromocytomas are rare tumors of the adrenal gland. Intestinal pseudo-obstruction is a very rare presentation of a functioning catecholamine-secreting tumor. We present a case of intestinal pseudo-obstruction due to a large functioning pheochromocytoma. CASE REPORT: A 29-year-old female presented with abdominal distension, pain, nausea, and vomiting with constipation for 3 weeks. She was hypertensive and diabetic and was on multiple medications. She reported frequent spells of severe headaches, palpitations, night sweats, and a 17 kg weight loss over 6 months. She had pallor, dyspnea, marked abdominal distension, and diminished bowel sounds. Her blood pressure was high at 200/120 mmHg. She had tachycardia (pulse 120 bpm) and tachypnea (35 pm). Serum metanephrine levels were significantly elevated, measuring 1203 pg/ml. Abdominal CT showed a heterogeneous, hyper-vascular mass near the upper pole of the left kidney, measuring 10.75 cm × 8.72 cm. Open left adrenalectomy was performed through an anterior subcostal approach to remove the tumor with the left adrenal gland. Histopathological examinations were consistent with pheochromocytoma. DISCUSSION: Some authors documented the correlation between tumor size and metabolic activity of catecholamine-secreting tumors with intestinal pseudo-obstruction by paralytic ileus. This case corresponds with these findings, with a tumor mass of 350 g and a serum metanephrine level of 1203 pg/ml. CONCLUSION: Although it is extremely rare, functioning pheochomocytoma could be a cause of instestinal obstruction or pseudo-obstruction. Elsevier 2022-04-04 /pmc/articles/PMC9043669/ /pubmed/35447562 http://dx.doi.org/10.1016/j.ijscr.2022.107008 Text en © 2022 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Case Report Bapir, Rawa Ahmed, Shaho F. Gharib, Soran Mohammeed Qader, Deedar Kakamad, Fahmi H. Popov, Elenko Buchholz, Noor Salih, Abduwahid M. Acute intestinal pseudo-obstruction by pheochromocytoma: A case report with review of literature |
title | Acute intestinal pseudo-obstruction by pheochromocytoma: A case report with review of literature |
title_full | Acute intestinal pseudo-obstruction by pheochromocytoma: A case report with review of literature |
title_fullStr | Acute intestinal pseudo-obstruction by pheochromocytoma: A case report with review of literature |
title_full_unstemmed | Acute intestinal pseudo-obstruction by pheochromocytoma: A case report with review of literature |
title_short | Acute intestinal pseudo-obstruction by pheochromocytoma: A case report with review of literature |
title_sort | acute intestinal pseudo-obstruction by pheochromocytoma: a case report with review of literature |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9043669/ https://www.ncbi.nlm.nih.gov/pubmed/35447562 http://dx.doi.org/10.1016/j.ijscr.2022.107008 |
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