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Intranasal Immunization With a c-di-GMP-Adjuvanted Acellular Pertussis Vaccine Provides Superior Immunity Against Bordetella pertussis in a Mouse Model

Pertussis, caused by the gram-negative bacterium Bordetella pertussis, is a highly contagious respiratory disease. Intranasal vaccination is an ideal strategy to prevent pertussis, as the nasal mucosa represents the first-line barrier to B. pertussis infection. The current intramuscular acellular pe...

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Detalles Bibliográficos
Autores principales:	Jiang, Wenwen, Wang, Xiaoyu, Su, Yuhao, Cai, Lukui, Li, Jingyan, Liang, Jiangli, Gu, Qin, Sun, Mingbo, Shi, Li
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9043693/ https://www.ncbi.nlm.nih.gov/pubmed/35493458 http://dx.doi.org/10.3389/fimmu.2022.878832

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