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Classic mechanisms and experimental models for the anti‐inflammatory effect of traditional Chinese medicine

Inflammation is a common disease involved in the pathogenesis, complications, and sequelae of a large number of related diseases, and therefore considerable research has been directed toward developing anti‐inflammatory drugs for the prevention and treatment of these diseases. Traditional Chinese me...

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Autores principales: Hongzhi, Du, Xiaoying, Hou, Yujie, Guo, Le, Chen, Yuhuan, Miao, Dahui, Liu, Luqi, Huang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9043716/
https://www.ncbi.nlm.nih.gov/pubmed/35412027
http://dx.doi.org/10.1002/ame2.12224
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author Hongzhi, Du
Xiaoying, Hou
Yujie, Guo
Le, Chen
Yuhuan, Miao
Dahui, Liu
Luqi, Huang
author_facet Hongzhi, Du
Xiaoying, Hou
Yujie, Guo
Le, Chen
Yuhuan, Miao
Dahui, Liu
Luqi, Huang
author_sort Hongzhi, Du
collection PubMed
description Inflammation is a common disease involved in the pathogenesis, complications, and sequelae of a large number of related diseases, and therefore considerable research has been directed toward developing anti‐inflammatory drugs for the prevention and treatment of these diseases. Traditional Chinese medicine (TCM) has been used to treat inflammatory and related diseases since ancient times. According to the review of abundant modern scientific researches, it is suggested that TCM exhibit anti‐inflammatory effects at different levels, and via multiple pathways with various targets, and recently a series of in vitro and in vivo anti‐inflammatory models have been developed for anti‐inflammation research in TCM. Currently, the reported classic mechanisms of TCM and experimental models of its anti‐inflammatory effects provide reference points and guidance for further research and development of TCM. Importantly, the research clearly confirms that TCM is now and will continue to be an effective form of treatment for many types of inflammation and inflammation‐related diseases.
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spelling pubmed-90437162022-04-28 Classic mechanisms and experimental models for the anti‐inflammatory effect of traditional Chinese medicine Hongzhi, Du Xiaoying, Hou Yujie, Guo Le, Chen Yuhuan, Miao Dahui, Liu Luqi, Huang Animal Model Exp Med Themed Section: Traditional Chinese Medicines and Natural Medicines Research Inflammation is a common disease involved in the pathogenesis, complications, and sequelae of a large number of related diseases, and therefore considerable research has been directed toward developing anti‐inflammatory drugs for the prevention and treatment of these diseases. Traditional Chinese medicine (TCM) has been used to treat inflammatory and related diseases since ancient times. According to the review of abundant modern scientific researches, it is suggested that TCM exhibit anti‐inflammatory effects at different levels, and via multiple pathways with various targets, and recently a series of in vitro and in vivo anti‐inflammatory models have been developed for anti‐inflammation research in TCM. Currently, the reported classic mechanisms of TCM and experimental models of its anti‐inflammatory effects provide reference points and guidance for further research and development of TCM. Importantly, the research clearly confirms that TCM is now and will continue to be an effective form of treatment for many types of inflammation and inflammation‐related diseases. John Wiley and Sons Inc. 2022-04-12 /pmc/articles/PMC9043716/ /pubmed/35412027 http://dx.doi.org/10.1002/ame2.12224 Text en © 2022 The Authors. Animal Models and Experimental Medicine published by John Wiley & Sons Australia, Ltd on behalf of The Chinese Association for Laboratory Animal Sciences. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Themed Section: Traditional Chinese Medicines and Natural Medicines Research
Hongzhi, Du
Xiaoying, Hou
Yujie, Guo
Le, Chen
Yuhuan, Miao
Dahui, Liu
Luqi, Huang
Classic mechanisms and experimental models for the anti‐inflammatory effect of traditional Chinese medicine
title Classic mechanisms and experimental models for the anti‐inflammatory effect of traditional Chinese medicine
title_full Classic mechanisms and experimental models for the anti‐inflammatory effect of traditional Chinese medicine
title_fullStr Classic mechanisms and experimental models for the anti‐inflammatory effect of traditional Chinese medicine
title_full_unstemmed Classic mechanisms and experimental models for the anti‐inflammatory effect of traditional Chinese medicine
title_short Classic mechanisms and experimental models for the anti‐inflammatory effect of traditional Chinese medicine
title_sort classic mechanisms and experimental models for the anti‐inflammatory effect of traditional chinese medicine
topic Themed Section: Traditional Chinese Medicines and Natural Medicines Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9043716/
https://www.ncbi.nlm.nih.gov/pubmed/35412027
http://dx.doi.org/10.1002/ame2.12224
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