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Assessment of Sustainable Elimination Criteria for Iodine Deficiency Disorders Recommended by International Organizations

Enormous efforts have been made to evaluate the worldwide prevention and control of iodine deficiency disorders (IDDs). This study evaluated China's achievements in IDD prevention and control against WHO criteria for sustainable elimination of IDD. The study sample consisted of 556,390 school-a...

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Autores principales: Fan, Lijun, Meng, Fangang, Sun, Qihao, Zhai, Yuqian, Liu, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9043767/
https://www.ncbi.nlm.nih.gov/pubmed/35495946
http://dx.doi.org/10.3389/fnut.2022.852398
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author Fan, Lijun
Meng, Fangang
Sun, Qihao
Zhai, Yuqian
Liu, Peng
author_facet Fan, Lijun
Meng, Fangang
Sun, Qihao
Zhai, Yuqian
Liu, Peng
author_sort Fan, Lijun
collection PubMed
description Enormous efforts have been made to evaluate the worldwide prevention and control of iodine deficiency disorders (IDDs). This study evaluated China's achievements in IDD prevention and control against WHO criteria for sustainable elimination of IDD. The study sample consisted of 556,390 school-aged children and 271,935 pregnant women enrolled in the 2018 China National IDD Surveillance. As a result, at the national level, median urine iodine concentration (MUIC) was 206.1 and 163.5 μg/l in children and in pregnant women, respectively. The proportion of households consuming adequate iodized salt (PHCAIS) was 90.2%. The prevalence rates of goiter in children and thyroid disease in pregnant women were 2.0 and 0.8%, respectively. MUIC showed significant non-linear increasing trends with increasing PHCAIS in both children and pregnant women. The prevalence of thyroid disease in pregnant women had a sharp decreasing trend with increasing PHCAIS. Of note, the prevalence of goiter in children and thyroid disease in pregnant women against MUIC both presented as significant U-shaped curves, with the lowest prevalence at 100–300 μg/l of MUIC in children and 150–250 μg/l in pregnant women. PHCAIS, MUIC, and the programmatic indicators at the national level were all above their cut-offs proposed in the 2007 Criteria. Evaluation by adding the prevalence of goiter (<5%) yielded the different results at the county level. Sustainable elimination of IDD has been achieved nationally. 2018 Chinese surveillance data support the expansion of global cut-offs for optimal iodine status in school-age children from 100–199 to 100–299 μg/l as recommended by others and the lower limit of MUIC (150 μg/l) in pregnant women also seems justified. Inclusion of goiter prevalence <5% in our analysis reduced the number of municipalities and counties which had achieved sustainable elimination of IDD.
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spelling pubmed-90437672022-04-28 Assessment of Sustainable Elimination Criteria for Iodine Deficiency Disorders Recommended by International Organizations Fan, Lijun Meng, Fangang Sun, Qihao Zhai, Yuqian Liu, Peng Front Nutr Nutrition Enormous efforts have been made to evaluate the worldwide prevention and control of iodine deficiency disorders (IDDs). This study evaluated China's achievements in IDD prevention and control against WHO criteria for sustainable elimination of IDD. The study sample consisted of 556,390 school-aged children and 271,935 pregnant women enrolled in the 2018 China National IDD Surveillance. As a result, at the national level, median urine iodine concentration (MUIC) was 206.1 and 163.5 μg/l in children and in pregnant women, respectively. The proportion of households consuming adequate iodized salt (PHCAIS) was 90.2%. The prevalence rates of goiter in children and thyroid disease in pregnant women were 2.0 and 0.8%, respectively. MUIC showed significant non-linear increasing trends with increasing PHCAIS in both children and pregnant women. The prevalence of thyroid disease in pregnant women had a sharp decreasing trend with increasing PHCAIS. Of note, the prevalence of goiter in children and thyroid disease in pregnant women against MUIC both presented as significant U-shaped curves, with the lowest prevalence at 100–300 μg/l of MUIC in children and 150–250 μg/l in pregnant women. PHCAIS, MUIC, and the programmatic indicators at the national level were all above their cut-offs proposed in the 2007 Criteria. Evaluation by adding the prevalence of goiter (<5%) yielded the different results at the county level. Sustainable elimination of IDD has been achieved nationally. 2018 Chinese surveillance data support the expansion of global cut-offs for optimal iodine status in school-age children from 100–199 to 100–299 μg/l as recommended by others and the lower limit of MUIC (150 μg/l) in pregnant women also seems justified. Inclusion of goiter prevalence <5% in our analysis reduced the number of municipalities and counties which had achieved sustainable elimination of IDD. Frontiers Media S.A. 2022-04-13 /pmc/articles/PMC9043767/ /pubmed/35495946 http://dx.doi.org/10.3389/fnut.2022.852398 Text en Copyright © 2022 Fan, Meng, Sun, Zhai and Liu. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Nutrition
Fan, Lijun
Meng, Fangang
Sun, Qihao
Zhai, Yuqian
Liu, Peng
Assessment of Sustainable Elimination Criteria for Iodine Deficiency Disorders Recommended by International Organizations
title Assessment of Sustainable Elimination Criteria for Iodine Deficiency Disorders Recommended by International Organizations
title_full Assessment of Sustainable Elimination Criteria for Iodine Deficiency Disorders Recommended by International Organizations
title_fullStr Assessment of Sustainable Elimination Criteria for Iodine Deficiency Disorders Recommended by International Organizations
title_full_unstemmed Assessment of Sustainable Elimination Criteria for Iodine Deficiency Disorders Recommended by International Organizations
title_short Assessment of Sustainable Elimination Criteria for Iodine Deficiency Disorders Recommended by International Organizations
title_sort assessment of sustainable elimination criteria for iodine deficiency disorders recommended by international organizations
topic Nutrition
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9043767/
https://www.ncbi.nlm.nih.gov/pubmed/35495946
http://dx.doi.org/10.3389/fnut.2022.852398
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