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Impact of Manufacturing Procedures on CAR T Cell Functionality

The field of chimeric antigen receptor (CAR) modified T cell therapy has rapidly expanded in the past few decades. As of today, there are six CAR T cell products that have been approved by the FDA: KYMRIAH (tisagenlecleucel, CD19 CAR T cells), YESCARTA (axicabtagene ciloleucel, CD19 CAR T cells), TE...

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Detalles Bibliográficos
Autores principales:	Watanabe, Norihiro, Mo, Feiyan, McKenna, Mary Kathryn
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9043864/ https://www.ncbi.nlm.nih.gov/pubmed/35493513 http://dx.doi.org/10.3389/fimmu.2022.876339

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