SORT1/LAMP2-mediated extracellular vesicle secretion and cell adhesion are linked to lenalidomide resistance in multiple myeloma

Multiple myeloma (MM) is a hematopoietic malignancy whose prognosis has improved with the development of new agents such as lenalidomide over the last decade. However, long-term exposure to drugs induces the acquisition of resistance by MM cells and leads to treatment failure and poor prognosis. Her...

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Detalles Bibliográficos
Autores principales: Yamamoto, Tomofumi, Nakayama, Jun, Yamamoto, Yusuke, Kuroda, Masahiko, Hattori, Yutaka, Ochiya, Takahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Hematology 2022
Materias:
Myeloid Neoplasia
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9043942/
https://www.ncbi.nlm.nih.gov/pubmed/34979567
http://dx.doi.org/10.1182/bloodadvances.2021005772

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9043942/
https://www.ncbi.nlm.nih.gov/pubmed/34979567
http://dx.doi.org/10.1182/bloodadvances.2021005772

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