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SORT1/LAMP2-mediated extracellular vesicle secretion and cell adhesion are linked to lenalidomide resistance in multiple myeloma
Multiple myeloma (MM) is a hematopoietic malignancy whose prognosis has improved with the development of new agents such as lenalidomide over the last decade. However, long-term exposure to drugs induces the acquisition of resistance by MM cells and leads to treatment failure and poor prognosis. Her...
Autores principales: | Yamamoto, Tomofumi, Nakayama, Jun, Yamamoto, Yusuke, Kuroda, Masahiko, Hattori, Yutaka, Ochiya, Takahiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Hematology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9043942/ https://www.ncbi.nlm.nih.gov/pubmed/34979567 http://dx.doi.org/10.1182/bloodadvances.2021005772 |
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