The TΑp63/BCL2 axis represents a novel mechanism of clinical aggressiveness in chronic lymphocytic leukemia

The TA-isoform of the p63 transcription factor (TAp63) has been reported to contribute to clinical aggressiveness in chronic lymphocytic leukemia (CLL) in a hitherto elusive way. Here, we sought to further understand and define the role of TAp63 in the pathophysiology of CLL. First, we found that el...

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Detalles Bibliográficos
Autores principales: Laidou, Stamatia, Grigoriadis, Dionysios, Papanikolaou, Sofia, Foutadakis, Spyros, Ntoufa, Stavroula, Tsagiopoulou, Maria, Vatsellas, Giannis, Anagnostopoulos, Achilles, Kouvatsi, Anastasia, Stavroyianni, Niki, Psomopoulos, Fotis, Makris, Antonios M., Agelopoulos, Marios, Thanos, Dimitris, Chatzidimitriou, Anastasia, Papakonstantinou, Nikos, Stamatopoulos, Kostas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Hematology 2022
Materias:
Lymphoid Neoplasia
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9043946/
https://www.ncbi.nlm.nih.gov/pubmed/35235952
http://dx.doi.org/10.1182/bloodadvances.2021006348

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