Efficacy of glucagon-like peptide-1 and estrogen dual agonist in pancreatic islets protection and pre-clinical models of insulin-deficient diabetes

We study the efficacy of a glucagon-like peptide-1 (GLP-1) and estrogen dual agonist (GLP1-E2) in pancreatic islet protection. GLP1-E2 provides superior protection from insulin-deficient diabetes induced by multiple low-dose streptozotocin (MLD-STZ-diabetes) and by the Akita mutation in mice than a...

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Autores principales: Fuselier, Taylor, Mota de Sa, Paula, Qadir, M.M. Fahd, Xu, Beibei, Allard, Camille, Meyers, Mathew M., Tiano, Joseph P., Yang, Bin S., Gelfanov, Vasily, Lindsey, Sarah H., Dimarchi, Richard D., Mauvais-Jarvis, Franck
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9043999/
https://www.ncbi.nlm.nih.gov/pubmed/35492248
http://dx.doi.org/10.1016/j.xcrm.2022.100598

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