Cargando…
YY1 Regulates Glucose Homeostasis Through Controlling Insulin Transcription in Pancreatic β-Cells
To date, identification of nonislet-specific transcriptional factors in the regulation of insulin gene expression has been little studied. Here, we report that the expression level of the transcription factor YY1 is increased dramatically in both human and mouse pancreatic β-cells after birth. Never...
Autores principales: | Liu, Di, Yang, Kevin Y., Chan, Vicken W., Ye, Wenchu, Chong, Charing C.N., Wang, Chi Chiu, Wang, Huating, Zhou, Bin, Cheng, Kenneth K.Y., Lui, Kathy O. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9044128/ https://www.ncbi.nlm.nih.gov/pubmed/35113157 http://dx.doi.org/10.2337/db21-0695 |
Ejemplares similares
-
Single-Cell RNA-Seq Reveals that CD9 Is a Negative Marker of Glucose-Responsive Pancreatic β-like Cells Derived from Human Pluripotent Stem Cells
por: Li, Xisheng, et al.
Publicado: (2020) -
Wld(S) Enhances Insulin Transcription and Secretion via a SIRT1-Dependent Pathway and Improves Glucose Homeostasis
por: Wu, Jingxia, et al.
Publicado: (2011) -
Overexpression of Kinase-Dead mTOR Impairs Glucose Homeostasis by Regulating Insulin Secretion and Not β-Cell Mass
por: Alejandro, Emilyn U., et al.
Publicado: (2017) -
Δ40 Isoform of p53 Controls β-Cell Proliferation and Glucose Homeostasis in Mice
por: Hinault, Charlotte, et al.
Publicado: (2011) -
Type 2 Diabetes–Associated K(+) Channel TALK-1 Modulates β-Cell Electrical Excitability, Second-Phase Insulin Secretion, and Glucose Homeostasis
por: Vierra, Nicholas C., et al.
Publicado: (2015)