Canagliflozin Prevents Hyperglycemia-Associated Muscle Extracellular Matrix Accumulation and Improves the Adaptive Response to Aerobic Exercise

Chronic hyperglycemia is associated with low response to aerobic exercise training in rodent models and humans, including reduced aerobic exercise capacity and impaired oxidative remodeling in skeletal muscle. Here, we investigated whether glucose lowering with the sodium–glucose cotransporter 2 inh...

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Detalles Bibliográficos
Autores principales: MacDonald, Tara L., Pattamaprapanont, Pattarawan, Cooney, Eileen M., Nava, Roberto C., Mitri, Joanna, Hafida, Samar, Lessard, Sarah J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2022
Materias:
Metabolism
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9044131/
https://www.ncbi.nlm.nih.gov/pubmed/35108373
http://dx.doi.org/10.2337/db21-0934

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