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Synthesis of quinolines via sequential addition and I(2)-mediated desulfurative cyclization

An efficient one-pot approach for the synthesis of quinolines from o-aminothiophenol and 1,3-ynone under mild conditions is disclosed. With the aid of ESI-MS analysis and parallel experiments, a three-step mechanism is proposed—a two-step Michael addition–cyclization condensation step leading to int...

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Detalles Bibliográficos
Autores principales: Yang, Mingming, Jian, Yajun, Zhang, Weiqiang, Sun, Huaming, Zhang, Guofang, Wang, Yanyan, Gao, Ziwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9044151/
https://www.ncbi.nlm.nih.gov/pubmed/35493239
http://dx.doi.org/10.1039/d1ra06976d

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