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Integrative genomic analysis reveals low T-cell infiltration as the primary feature of tobacco use in HPV-positive oropharyngeal cancer

Although tobacco use is an independent adverse prognostic feature in HPV(+) oropharyngeal squamous cell carcinoma (OPSCC), the biologic features associated with tobacco use have not been systematically investigated. We characterized genomic and immunologic features associated with tobacco use throug...

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Detalles Bibliográficos
Autores principales:	Wahle, Benjamin M., Zolkind, Paul, Ramirez, Ricardo J., Skidmore, Zachary L., Anderson, Sydney R., Mazul, Angela, Hayes, D. Neil, Sandulache, Vlad C., Thorstad, Wade L., Adkins, Douglas, Griffith, Obi L., Griffith, Malachi, Zevallos, Jose P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9044176/ https://www.ncbi.nlm.nih.gov/pubmed/35494251 http://dx.doi.org/10.1016/j.isci.2022.104216

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