Graphene oxide-catalyzed trifluoromethylation of alkynes with quinoxalinones and Langlois' reagent

The direct C–H trifluoromethylation of alkynes and quinoxalinones has been achieved using a graphene oxide/Langlois' reagent system. This multi-component tandem reaction using graphene oxide as the catalyst and Langlois' reagent as the robust CF(3) radical source results in the formation o...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Hong, Peng, Xiangjun, Nie, Liang, Zhou, Lin, Yang, Ming, Li, Fan, Hu, Jian, Yao, Zhiyang, Liu, Liangxian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9044184/
https://www.ncbi.nlm.nih.gov/pubmed/35493205
http://dx.doi.org/10.1039/d1ra07014b
_version_ 1784695048959426560
author Li, Hong
Peng, Xiangjun
Nie, Liang
Zhou, Lin
Yang, Ming
Li, Fan
Hu, Jian
Yao, Zhiyang
Liu, Liangxian
author_facet Li, Hong
Peng, Xiangjun
Nie, Liang
Zhou, Lin
Yang, Ming
Li, Fan
Hu, Jian
Yao, Zhiyang
Liu, Liangxian
author_sort Li, Hong
collection PubMed
description The direct C–H trifluoromethylation of alkynes and quinoxalinones has been achieved using a graphene oxide/Langlois' reagent system. This multi-component tandem reaction using graphene oxide as the catalyst and Langlois' reagent as the robust CF(3) radical source results in the formation of olefinic C–CF(3) to access a series of 3-trifluoroalkylated quinoxalin-2(1H)-ones.
format Online
Article
Text
id pubmed-9044184
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher The Royal Society of Chemistry
record_format MEDLINE/PubMed
spelling pubmed-90441842022-04-28 Graphene oxide-catalyzed trifluoromethylation of alkynes with quinoxalinones and Langlois' reagent Li, Hong Peng, Xiangjun Nie, Liang Zhou, Lin Yang, Ming Li, Fan Hu, Jian Yao, Zhiyang Liu, Liangxian RSC Adv Chemistry The direct C–H trifluoromethylation of alkynes and quinoxalinones has been achieved using a graphene oxide/Langlois' reagent system. This multi-component tandem reaction using graphene oxide as the catalyst and Langlois' reagent as the robust CF(3) radical source results in the formation of olefinic C–CF(3) to access a series of 3-trifluoroalkylated quinoxalin-2(1H)-ones. The Royal Society of Chemistry 2021-12-01 /pmc/articles/PMC9044184/ /pubmed/35493205 http://dx.doi.org/10.1039/d1ra07014b Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by/3.0/
spellingShingle Chemistry
Li, Hong
Peng, Xiangjun
Nie, Liang
Zhou, Lin
Yang, Ming
Li, Fan
Hu, Jian
Yao, Zhiyang
Liu, Liangxian
Graphene oxide-catalyzed trifluoromethylation of alkynes with quinoxalinones and Langlois' reagent
title Graphene oxide-catalyzed trifluoromethylation of alkynes with quinoxalinones and Langlois' reagent
title_full Graphene oxide-catalyzed trifluoromethylation of alkynes with quinoxalinones and Langlois' reagent
title_fullStr Graphene oxide-catalyzed trifluoromethylation of alkynes with quinoxalinones and Langlois' reagent
title_full_unstemmed Graphene oxide-catalyzed trifluoromethylation of alkynes with quinoxalinones and Langlois' reagent
title_short Graphene oxide-catalyzed trifluoromethylation of alkynes with quinoxalinones and Langlois' reagent
title_sort graphene oxide-catalyzed trifluoromethylation of alkynes with quinoxalinones and langlois' reagent
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9044184/
https://www.ncbi.nlm.nih.gov/pubmed/35493205
http://dx.doi.org/10.1039/d1ra07014b
work_keys_str_mv AT lihong grapheneoxidecatalyzedtrifluoromethylationofalkyneswithquinoxalinonesandlangloisreagent
AT pengxiangjun grapheneoxidecatalyzedtrifluoromethylationofalkyneswithquinoxalinonesandlangloisreagent
AT nieliang grapheneoxidecatalyzedtrifluoromethylationofalkyneswithquinoxalinonesandlangloisreagent
AT zhoulin grapheneoxidecatalyzedtrifluoromethylationofalkyneswithquinoxalinonesandlangloisreagent
AT yangming grapheneoxidecatalyzedtrifluoromethylationofalkyneswithquinoxalinonesandlangloisreagent
AT lifan grapheneoxidecatalyzedtrifluoromethylationofalkyneswithquinoxalinonesandlangloisreagent
AT hujian grapheneoxidecatalyzedtrifluoromethylationofalkyneswithquinoxalinonesandlangloisreagent
AT yaozhiyang grapheneoxidecatalyzedtrifluoromethylationofalkyneswithquinoxalinonesandlangloisreagent
AT liuliangxian grapheneoxidecatalyzedtrifluoromethylationofalkyneswithquinoxalinonesandlangloisreagent

Ejemplares similares