Application of Pauson–Khand reaction in the total synthesis of terpenes

The Pauson–Khand reaction (PKR) is a formal [2 + 2 + 1] cycloaddition involving an alkyne, an alkene and carbon monoxide mediated by a hexacarbonyldicobaltalkyne complex to yield cyclopentenones in a single step. This versatile reaction has become a method of choice for the synthesis of cyclopenteno...

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Detalles Bibliográficos
Autores principales: Heravi, Majid M., Mohammadi, Leila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9044263/
https://www.ncbi.nlm.nih.gov/pubmed/35493249
http://dx.doi.org/10.1039/d1ra05673e
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author Heravi, Majid M.
Mohammadi, Leila
author_facet Heravi, Majid M.
Mohammadi, Leila
author_sort Heravi, Majid M.
collection PubMed
description The Pauson–Khand reaction (PKR) is a formal [2 + 2 + 1] cycloaddition involving an alkyne, an alkene and carbon monoxide mediated by a hexacarbonyldicobaltalkyne complex to yield cyclopentenones in a single step. This versatile reaction has become a method of choice for the synthesis of cyclopentenone and its derivatives since its discovery in the early seventies. The aim of this review is to point out the applications of PKR in the total synthesis of terpenes.
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spelling pubmed-90442632022-04-28 Application of Pauson–Khand reaction in the total synthesis of terpenes Heravi, Majid M. Mohammadi, Leila RSC Adv Chemistry The Pauson–Khand reaction (PKR) is a formal [2 + 2 + 1] cycloaddition involving an alkyne, an alkene and carbon monoxide mediated by a hexacarbonyldicobaltalkyne complex to yield cyclopentenones in a single step. This versatile reaction has become a method of choice for the synthesis of cyclopentenone and its derivatives since its discovery in the early seventies. The aim of this review is to point out the applications of PKR in the total synthesis of terpenes. The Royal Society of Chemistry 2021-11-29 /pmc/articles/PMC9044263/ /pubmed/35493249 http://dx.doi.org/10.1039/d1ra05673e Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by/3.0/
spellingShingle Chemistry
Heravi, Majid M.
Mohammadi, Leila
Application of Pauson–Khand reaction in the total synthesis of terpenes
title Application of Pauson–Khand reaction in the total synthesis of terpenes
title_full Application of Pauson–Khand reaction in the total synthesis of terpenes
title_fullStr Application of Pauson–Khand reaction in the total synthesis of terpenes
title_full_unstemmed Application of Pauson–Khand reaction in the total synthesis of terpenes
title_short Application of Pauson–Khand reaction in the total synthesis of terpenes
title_sort application of pauson–khand reaction in the total synthesis of terpenes
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9044263/
https://www.ncbi.nlm.nih.gov/pubmed/35493249
http://dx.doi.org/10.1039/d1ra05673e
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